PUBLICATIONS

  1. Pachetti M, Marini B, Benedetti F, Giudici F, Mauro E, Storici P, Masciovecchio C, Angeletti S, Ciccozzi M, Gallo RC, Zella D, Ippodrino R.J. “Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant.” Transl Med. 2020 Apr 22;18(1):179. doi: 10.1186/s12967-020-02344-6.
  2. Cavalloro V, Russo K, Vasile F, Pignataro L, Torretta A, Donini S, Semrau MS, Storici P, Rossi R, Rapetti R, Brullo C, Parisini E, Bruno O, Collina S. Insight into GEBR-32a: Chiral Resolution, Absolute Configuration and Enantiopreference in PDE4D Inhibition. Molecules. 2020;25(4):E935. Published 2020 Feb 19. doi:10.3390/molecules2504093
  3. Veggiani G, Giabbai B, Semrau MS, Medagli B, Riccio V, Bajc G, Storici P, de Marco A. Comparative analysis of fusion tags used to functionalize recombinant antibodies. Protein Expr Purif. 2020 Feb;166:105505. doi: 10.1016/j.pep.2019.105505. Epub 2019 Sep 26.
  4. Soler MA, Medagli B, Semrau MS, Storici P, Bajc G, de Marco A, Laio A, Fortuna S. A consensus protocol for the in silico optimisation of antibody fragments. 2019 Chem Commun (Camb). Nov 19;55(93):14043-14046. doi: 10.1039/c9cc06182g
  5. Rosa B, Marchetti M, Paredi G, Amenitsch H, Franko N, Benoni R, Giabbai B, De Marino MG, Mozzarelli A, Ronda L, Storici P, Campanini B, Bettati S. Combination of SAXS and protein painting discloses the three-dimensional organization of the bacterial cysteine synthase complex, a potential target for enhancers of antibiotic action. Int J Mol Sci. 2019 Oct 21;20(20):5219. doi: 10.3390/ijms20205219.
  6. Gobbo D, Piretti V, Di Martino RMC, Tripathi SK, Giabbai B, Storici P, Demitri N, Girotto S, Decherchi S, and Cavalli A. Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations. J. Chem. Theory Comput., 2019 Aug 13:15 (8) 4646-4659, DOI: 10.1021/acs.jctc.9b00104.
  7. Redenti S, Marcovich I, De Vita T, Perez C, De Zorzi R, Demitri N, Perez DI, Bottegoni G, Bisignano P, Bissaro M, Moro S, Martinez A, Storici P, Spalluto G, Cavalli A, and Federico S. A Triazolotriazine-based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. 2019 Feb 5;14(3):310-314 ChemMedChem 10.1002/cmdc.201800778
  8. Carlino L, Christodoulou MS, Restelli V, Caporuscio F, Foschi F, Semrau MS, Costanzi E, Tinivella A, Pinzi L, Lo Presti L, Battistutta R, Storici P, Broggini M, Passarella D, Rastelli G. Structure-Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR. ChemMedChem. 2018 Nov 20. doi: 10.1002/cmdc.201800687.
  9. Raboni S, Revtovich S, Demitri N, Giabbai B, Storici P, Cocconcelli C, Faggiano S, Rosini E, Pollegioni L, Galati S, Buschini A, Morozova E, Kulikova V, Nikulin A, Gabellieri E, Cioni P, Demidkina T, Mozzarelli A. Engineering methionine γ-lyase from Citrobacter freundii for anticancer activity. Biochim Biophys Acta Proteins Proteom. 2018 Dec;1866(12):1260-1270. doi: 10.1016/j.bbapap.2018.09.011. Epub 2018 Sep 27.
  10. Prosdocimi T, Mollica L, Donini S, Semrau MS, Lucarelli AP, Aiolfi E, Cavalli A, Storici P, Alfei S, Brullo C, Bruno O, Parisini E. Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds. Biochemistry. 2018 May 15;57(19):2876-2888. doi: 10.1021/acs.biochem.8b00288. Epub 2018 May 1.
  11. Caporuscio F, Tinivella A, Restelli V, Semrau MS, Pinzi L, Storici P, Broggini M, Rastelli G. Identification of small-molecule EGFR allosteric inhibitors by high-throughput docking. Future Med Chem. 2018 May 16. doi: 10.4155/fmc-2018-0063. PubMed PMID: 29766737.
  12. Stolt-Bergner P, Benda C, Bergbrede T, Besir H, Celie PHN, Chang C, Drechsel D, Fischer A, Geerlof A, Giabbai B, van den Heuvel J, Huber G, Knecht W, Lehner A, Lemaitre R, Nordén K, Pardee G, Racke I, Remans K, Sander A, Scholz J, Stadnik M, Storici P, Weinbruch D, Zaror I, Lua LHL, Suppmann S., (2018), Baculovirus-driven protein expression in insect cells: A benchmarking study. J Struct Biol. Mar 12. pii: S1047-8477(18)30066-2. doi: 10.1016/j.jsb.2018.03.004.
  13. Campaner E., Rustighi A., Zannini A., Cristiani A., Piazza S., Ciani Y., Kalid O., Golan G., Baloglu E., Shacham S., Valsasina B., Cucchi U., Pippione A.C., Lolli M., Giabbai B., Storici P., Carloni P., Rossetti G., Bello E., D’Incalci M., Sommaggio R., Cappuzzello E., Rosato A., and Del Sal G. A new covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action; Nat Commun. 2017 Jun 9;8:15772. doi: 10.1038/ncomms15772.
  14. Basters A., Geurink sP.P., Röcker A., Witting K.F., Tadayon R., Hess S., Semrau M.S., Storici P., Ovaa H., Knobeloch K-P, and Fritz G.; Structural basis for the specificity of USP18 towards ISG15, Nat Struct Mol Biol. 2017 Mar;24(3):270-278. doi: 10.1038/nsmb.3371.
  15. Kenig S, Faoro V, Bourkoula E, Podergajs N, Ius T, Vindigni M, Skrap M, Lah T, Cesselli D, Storici P, Vindigni A.; Topoisomerase IIβ mediates the resistance of glioblastoma stem cells to replication stress-inducing drugs. Cancer Cell Int. 2016 Jul 26;16:58. doi: 10.1186/s12935-016-0339-9.
  16. Kenig S, Bedolla DE, Birarda G, Faoro V, Mitri E, Vindigni A, Storici P, Vaccari L.; Fourier transform infrared microspectroscopy reveals biochemical changes associated with glioma stem cell differentiation. Biophys Chem. 2015 Dec;207:90-6. doi: 10.1016/j.bpc.2015.09.005. Epub 2015 Sep 25.
  17. Gianoncelli A, Vaccari L, Kourousias G, Cassese D, Bedolla DE, Kenig S, Storici P, Lazzarino M, Kiskinova M. Soft X-Ray Microscopy Radiation Damage On Fixed Cells Investigated With Synchrotron Radiation FTIR Microscopy. Sci Rep. 2015 May 14;5:10250. doi: 10.1038/srep10250.
  18. Cersosimo U., Sgorbissa A., Foti C., Drioli S., Angelica R., Tomasella A., Picco R., Semrau M., Storici P., Benedetti F., Berti F., Brancolini C.; Synthesis, Characterization and Optimization for in Vivo Delivery of a Non-Selective Isopeptidase Inhibitor as New Anti-Neoplastic Agent. J Med Chem. 2015 Feb 26;58(4):1691-704. doi: 10.1021/jm501336h.
  19. Ronda L, Bruno S, Bettati S, Storici P, Mozzarelli A.; From protein structure to function via single crystal optical spectroscopy. Front Mol Biosci. 2015 Apr 28;2:12. doi: 10.3389/fmolb.2015.00012.
  20. Bedolla D, Kenig S, Mitri E, Storici P, Vaccari L; Further insights into G1 and G0 phases of cell cycle revealed by FTIR microspectroscopy. Vib. Spec. 75: 127-135. DOI: 10.1016/j.vibspec.2014.08.007 – 2014
  21. Bindi S, Fancelli D, Alli C, Berta D, Bertrand JA, Cameron AD, Cappella P, Carpinelli P, Cervi G, Croci V, D'Anello M, Forte B, Giorgini ML, Marsiglio A, Moll J, Pesenti E, Pittalà V, Pulici M, Riccardi-Sirtori F, Roletto F, Soncini C, Storici P, Varasi M, Volpi D, Zugnoni P, Vianello P. Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity. Bioorg Med Chem. 2010 Oct 1;18(19):7113-20.
  22. Beria I, Ballinari D, Bertrand JA, Borghi D, Bossi RT, Brasca MG, Cappella P, Caruso M, Ceccarelli W, Ciavolella A, Cristiani C, Croci V, De Ponti A, Fachin G, Ferguson RD, Lansen J, Moll JK, Pesenti E, Posteri H, Perego R, Rocchetti M, Storici P, Volpi D and Valsasina B; Identification of 4,5-Dihydro-1H-pyrazolo[4,3-h]quinazoline Derivatives as a New Class of Orally and Selective Polo-Like Kinase 1 Inhibitors. J Med Chem. 2010 May 13;53(9):3532-51.
  23. Carpinelli P, Ceruti R, Giorgini ML, Cappella P, Gianellini L, Croci V, Degrassi A, Texido G, Rocchetti M, Vianello P, Rusconi L, Storici P, Zugnoni P, Arrigoni C, Soncini C, Alli C, Patton V, Marsiglio A, Ballinari D, Pesenti E, Fancelli D, Moll J. (2007) PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer. Mol. Cancer Ther.; 6(12 Pt 1):3158-68.
  24. Fancelli D, Moll J, Varasi M, Bravo R, Artico R, Berta D, Bindi S, Cameron A, Candiani I, Cappella P, Carpinelli P, Croci W, Forte B, Giorgini ML, Klapwijk J, Marsiglio A, Pesenti E, Rocchetti M, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Zugnoni P, and Vianello P (2006) 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: Identification of a Potent Aurora Kinases Inhibitor with a Favorable Antitumor Kinase Inhibition Profile, J Med Chem.; 49(24):7247-51.
  25. Soncini C, Carpinelli P, Giannellini L, Fancelli D, Vianello P, Rusconi L, Storici P, Zugnoni P, Pesenti E, Croci V, Ceruti R, Giorgini ML, Cappella P, Ballinari D, Sola F, Varasi M & Bravo R (2006), PHA680632, a novel Aurora kinase inhibitor with potent antitumoral activity Clin.Cancer Res. 12(13): 4080-4090.
  26. Baslé A, Rummel G, Storici P, Rosenbusch J.P .and Schirmer T (2006), X-ray crystal structure of osmoporin OmpC from E. coli at 2.0 Å. J.Mol.Biol.362(5):933-942
  27. Fancelli D, Berta D, Bindi S, Cameron A, Cappella P, Carpinelli P, Catana C, Forte B, Giordano P, Giorgini ML, Mantegani S, Marsiglio A, Meroni M, Moll J, Pittala V, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Varasi M, Vulpetti A, Vianello P. (2005) Potent and selective aurora inhibitors identified by the expansion of a novel scaffold for protein kinase inhibition. J Med Chem. 48(8): 3080-3084.
  28. Storici P, Qiu J, Schirmer T, Silverman RB. (2004) Mechanistic crystallography. Mechanism of inactivation of gamma-aminobutyric acid aminotransferase by (1R,3S,4S)-3-amino-4-fluorocyclopentane-1-carboxylic acid as elucidated by crystallography. Biochemistry. 43(44):14057-14063
  29. Storici P., De Biase D., Bossa F., Bruno, S., Mozzarelli A., Peneff C., Silverman R.B. and Schirmer T. (2004) Structures of g-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin. J Biol Chem. 279:363-373. Epub 2003 Oct 08.
  30. Lolli G, Thaler F, Valsasina B, Roletto F, Knapp S, Uggeri M, Bachi A, Matafora V, Storici P., Stewart A, Kalisz HM, Isacchi A. (2003) Inhibitor affinity chromatography: profiling the specific reactivity of the proteome with immobilized molecules. Proteomics. Jul;3(7):1287-1298
  31. Choi S., Storici P., Schirmer T. and Silverman R.B. (2002) Design of a conformationally restricted analogue of the antiepilepsy drug Vigabatrin that directs its mechanism of inactivation of gamma-aminobutyric acid aminotransferase. J Am Chem Soc. 124:1620-1624.
  32. Capitani, G., Hohenester, E., Feng, L., Storici, P., Kirsh, J.F. and Jansonius, J.N. (1999) Structure of 1-aminocyclopropane-1-carboxylatesynthase, a key enzyme in the biosynthesis of the plant hormone ethylene. J.Mol.Biol. 294: 743-755.
  33. Bordo, D., Colnaghi R., Deriu, R., Carpen, A., Storici, P., Pagani, S. amd Bolognesi, M. (1999) Crystallization and preliminary Crystallographiv investigations of rhodanese from Azotobacter vinelandii Acta Cryst.D55:1471-1473
  34. Storici,P., Capitani, G., De Biase, D., Moser, M., John, R.J. Jansonius, J.N., and Schirmer, T. (1999) Crystal Structure of GABA-aminotransferase, a target for antiepileptic drug therapy, Biochemistry 38 8628-8634.
  35. Storici,P., Capitani, G., Mueller, R., Schirmer, T. and Jansonius, J.N. (1999) Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. J. Mol. Biol. 285: 297-309.
  36. Storici, P., Capitani, G., Mueller, R. and Jansonius, J.N.(1996) Structural studies of ornithine aminotransferase complexed with substrates and inhibitors: clarifying the reaction mechanism, DESY Annual Report, pp. 457-458.A.
  37. Storici, P., Tossi, A., Lenarcic, B. and Romeo, D. (1996)"Purification and structural characterization of bovine cathelincidins, precursors of antimicrobial peptides", Eur. J. Biochem. 238:769-776
  38. Romeo, D., Gennaro, R., Zanetti, M., Tossi, A., Skerlavaj, B., Storici, P., Scocchi, M., Litteri, L., and Verbanac, D. (1995) "Bovine neutrophil antibiotic peptides and their precursors: structure and role In innate immunity", Croat. Chem. Acta 68:607-614.
  39. Tossi, A., Scocchi, M., Zanetti, M., Storici, P. and Gennaro, R. (1995) "Porcine myeloid antimicrobial peptide, PMAP-37, a novel antimicrobial peptide from pig myeloid cells: cDNA cloning, chemical synthesis and activity", Eur. J. Biochem. 228: 941-946.
  40. Gennaro, R., Zanetti, M., Storici, P., Scocchi, M. and Tossi, A. (1994) "Synthesis and characterization of a novel pig antimicrobial peptide deduced from cDNA", Proc. of 23rd European Peptide Symposium (Braga, Portugal), pp. 3-1.
  41. Gennaro, R., Scocchi, M., Storici, P., A. Tossi, Skerlavaj, B., Bagella, L., Risso, A.., Romeo, D. and Zanetti, M. (1995) "Chemical synthesis, structural features and biological activity of novel mammalian antibiotic peptides identified through amplification of homologous cDNA sequences", Minerva Biotec 7:67-73.
  42. Zanetti, M., Storici, P., Tossi, A., Scocchi, M. and Gennaro,R. (1994) "Molecular cloning and chemical synthesis of a novel antimicrobial peptide derived from pig myeloid cells", J. Biol. Chem., 269: 7855-7858.
  43. Storici, P., Scocchi, M., Tossi, A., Gennaro, R. and Zanetti, M. (1994) "Chemical synthesis and biological activity of a novel antimicrobial peptide deduced from a pig myeloid cDNA" FEBS Lett., 337: 303-307.
  44. Storici, P. and Zanetti, M. (1993) "A novel cDNA sequence encoding a pig antimicrobial peptide with a cathelin-like pro-sequence", Biochem. Biophys. Res. Commun., 196:1363-1368.
  45. Storici, P. and Zanetti, M. (1993) "A cDNA derived from pig bone marrow cells contains a sequence identical to the intestinal antimicrobial peptide PR-39", Biochem. Biophys. Res. Commun., 196: 1058-1065.
  46. Zanetti, M., Del Sal, G., Storici, P., C., Schneider, and Romeo, D. (1993) "The cDNA of the neutrophil antibiotic Bac5 predicts a pro-sequence homologous to a cysteine proteinase inhibitor, that is common to other neutrophil antibiotics", J. Biol. Chem., 268: 522-526.
  47. Storici, P., Del Sal, G., Schneider, C., and Zanetti, M. (1992) "cDNA sequence analysis of an antibiotic dodecapeptide from neutrophils", FEBS lett., 314: 187-190.
  48. Del Sal, G., Storici, P., Schneider, C., Romeo, D. and Zanetti, M. (1992)"cDNA cloning of the Neutrophil Bactericidal Peptide Indolicidin", Biochem. Biophys. Res. Commun., 187: 467-472.

BOOK CHAPTERS

  1. Tossi, M. Scocchi, M. Zanetti, R. Gennaro, P.Storici and D. Romeo (1997) "An approach combining rapid cDNA amplification and chemical synthesis for the identification of novel, cathelicidin-derived, antimicrobial peptides", in: Antimicrobial Peptide Protocols - Methods in Molecular Biology (W.M. Shafer, ed.), Humana Press, Totowa, Vol 78 p 135.
  2. Storici, P., Capitani, G., De Biase, D., John, R.A., Jansonius J.N. and Schirmer, T. (2000) GABA-aminotransferase, a target for antiepileptic drug therapy, In book Biochemistry of Vitamin B6 and PQQ (Martinez-Carrion M. ed.) Birkhäuser Verlag, Basel.

last update May 23, 2020, at 12:43 PM by Paola Storici