Andrea Flores-Ibarra, PhD
EDUCATION AND WORK SUMMARY:
- Postdoctoral Researcher, Elettra Sincrotrone Trieste, as part of the project 'Transglioma', Jun 2019-current (https://www.ita-slo.eu/it/transglioma).
- Researcher Assistant, Autonomous University of Mexico, Jan 2019-May 2019.
- Clinical Consultant, Becton Dickinson, Nov 2017-Dec 2018.
- PhD in Molecular Biosciences, Autonomous University of Madrid, Oct 2017.
- Marie Curie Early Stage Researcher, Initial Training Network, Center for Biological Research (CSIC, Madrid), as part of the project ‘Glycopharm’, 2013-2016 (https://www.glycopharm.eu).
- Master’s Degree in Biophysics, Complutense University of Madrid, Jul 2015.
- H. Bachelor’s Degree in Medicinal Chemistry, Autonomous University of Puebla, Dec 2012.
Languages: English and Spanish (level bilingual), French (level B1), Italian (level B1).
PUBLICATIONS:
On the development of the elucidation for an oligomeric structure of Galectin-3 by X-ray crystallography, SAXS and biochemical-based modelling.
https://www.nature.com/articles/s41598-018-28235-x
https://onlinelibrary.wiley.com/iucr/doi/10.1107/S2053230X15000023
On the elucidation of C-Galectin-Related Protein and its lack of beta-galactoside ligands binding ability.
https://www.sciencedirect.com/science/article/pii/S0304416516302057?via%3Dihub
On the design and patent of polyolefin devices to transport crystallization boxes to synchrotron facilities at room temperature.
https://www.mdpi.com/2073-4352/8/9/340/htm
Book: "Structural characterization of Galectin-3 and Galectin-Related Protein by X-ray crystallography."
https://www.amazon.com/Structural-characterization-Galectins-Galectin-Related-Protein/dp/6139825407
Paperback
ISBN-10: 6139825407
ISBN-13: 978-6139825400
Product Dimensions: 5.9 x 0.3 x 8.7 inches
MAIN SKILLS:
- Macromolecules crystallization methods, vapor diffusion and capillary counter-diffusion. Design of crystal optimization conditions. Structural resolution of macromolecules by synchrotron X-ray diffraction analysis (X-ray crystallography), small-angle X-ray scattering, circular dichroism and analytical ultracentrifugation.
- Data processing and resolution of X-ray diffraction patterns through specialized software (XDS, CCP4i, Phenix, Coot and PyMol in Linux O.S.), of SAXS data (ATSAS software) and molecular modelling. Statistical analysis with Excel and R.
- Protein purification and characterization techniques, affinity and molecular exclusion chromatography, electrophoresis, FPLC, HPLC, MALDI-TOF.
- Recombinant DNA design, mutagenesis, genomic DNA isolation and digestion, cell transformation and cell cultures.
- Animal models (handling, inoculation and basic principles of surgery) for experimentation.
- Medicinal chemistry techniques in the areas of biochemistry and hematology.
OTHER INFO:
ORCID NO.:
https://orcid.org/0000-0003-2278-4558
RESEARCHGATE:
https://www.researchgate.net/profile/Andrea_Flores-Ibarra
LINKEDIN:
https://www.linkedin.com/in/andreafloresibarra/
