Seminars Archive

Chiral-label-free surface-enhanced Raman scattering strategy for the synchronous chiral discrimination and identification of aromatic molecules

Abstract
A chiral discrimination strategy for small aromatic compounds is very important for various research fields. However, most current methods do not have either the sufficient sensitivity for recognizing the chirality of
the target molecules or their molecular specificity information. We have developed a versatile and chiral-label-free surface-enhanced Raman scattering (SERS)-based chiral discrimination sensing system for small aromatic molecules, where the molecular structural specificity and enantioselectivity can be given synchronously in a single SERS spectrum. More than 10 types of chiral aromatic molecules were successfully identified using this system. This work has enormous potential for recognizing chiral products effectively in sophisticated systems, especially in the fields of chiral synthesis and chiral catalysis.