The AntiHelix consortium includes five renowned academic laboratories with a long-standing interest in the field of DNA helicases (CNR,
UCPH, USFD, ELETTRA, SLU), with a wide range of technical and scientific expertises, ranging from cell biology to biochemistry to structural biology, and working on different but interconnected DNA helicases; one world leader in the field of single molecules biophysical studies of protein-DNA interaction (VU); one research group dedicated to clinical oncology studies (UKESSEN); three companies involved in various stages of drug discovery (LDC, EDELRIS, PPSC) and one company developing state-of-the-art instrumentation for biophysical studies (LUMICKS).
This web of research groups and institutions will provide a thriving and innovative scientific environment that potentially offers unique opportunities to develop a strong research programme at the interface between different disciplines (cell biology, biochemistry, structural biology, biophysics, single molecule approaches, optics, medicinal chemistry, drug design, computational biology/chemistry, clinical oncology) with complementary experimental approaches and a strong emphasis on translation of scientific results.
Beneficiaries
- Istituto di Biochimica e Biologia Cellulare del Consiglio Nazionale delle Ricerche, Naples, IT (CNR) - Coordinator
- Elettra - Sincrotrone Trieste, IT (ELETTRA)
- University of Copenhagen, DK (UCPH)
- Vrije Universiteit Amsterdam, NL (STICHTING VU)
- University of Sheffield, UK (USFD)
- University Hospital University of Duisburg-Essen, DE (UKESSEN)
- Lead Discovery Center GmbH, Dortmund, DE (LDC)
- Edelris SAS, Lyon, FR (EDELRIS)
- Lumicks BV, Amsterdam, NL (LUMICKS)
Partners
- Washington University, Saint Louis, US (WUSTL)
- SISSA Medialab, Trieste, IT (SISSA ML)
- Università degli Studi della Campania Luigi Vanvitelli, Caserta, IT (UVAN, https://www.unicampania.it/)
- Université Grenoble Alpes, Grenoble, FR (UGA, https://www.univ-grenoble-alpes.fr/)
- Università degli studi Trieste, IT (UniTS, https://web.units.it/dottorato/chimica/en/node/7638)
Project Officers: Mattia Zilli and Giuliana Donini
Coordinator: Francesca Pisani
Deputy Coordinator: Ian Hickson
Training Coordinator: Ying Liu
Website Manager and Outreach Coordinator: Silvia Onesti
Supervisory Board
Voting members:
CNR | Francesca M. Pisani |
ELETTRA | Silvia Onesti |
UCPH | Ying Liu |
VU | Gijs Wuite |
USFD | Cyril Sanders |
UKESSEN | Iris Helfrich |
LCD | Bert Klebl |
EDELRIS | Didier Roche |
LUMICKS | Mattijs de Groot |
ESR Rep1 | Francesca Scommegna |
ESR Rep2 | Mark Wever |
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Non-voting members:
WUSTL | Alessandro Vindigni |
SISSA ML | Simona Cerrato |
UVAN | Andrea Riccio |
UGA | Jean Francois Poisson |
UniTS | Enzo Alessio |
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