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Breast computed tomography with the PICASSO detector: A feasibility study

The SYRMEP (Synchrotron Radiation for Medical Physics) collaboration has performed, for the first time in the world, a clinical program of mammography with synchrotron radiation.

  L. Rigon et. al. Nuclear Instruments and Methods in Physics Research A 628 (2011) 419–422

The SYRMEP (Synchrotron Radiation for Medical Physics) collaboration has performed, for the first time in the world, a clinical program of mammography with synchrotron radiation. This program provided
excellent results, although utilizing a commercial screen-film system as a detector. The PICASSO (Phase Imaging for Clinical Application with Silicon detector and Synchrotron radiation) project has developed a detector prototype capable of fully exploiting the peculiar characteristics of the synchrotron source, utilizing silicon microstrip sensors illuminated in the edge-on geometry and operated in single-photon counting. In this paper the potential of the PICASSO detector in breast computed tomography was
evaluated by means of custom phantoms. Very encouraging results have been obtained with severe dose constrains as far as both spatial and contrast resolution are concerned. Moreover, the capability of detecting phase contrast effects was demonstrated, albeit with a higher delivered dose.

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Breast computed tomography with the PICASSO detector: A feasibility study
Luigi Rigon, Federica Tapete, Diego Dreossi, Fulvia Arfelli, Anna Bergamaschi, Rong-Chang Chen , Renata Longo, Ralf-Hendrik Menk, Bernd Schmitt, Erik Vallazza , Edoardo Castelli , doi link
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