XRD2 Publications

A list of publications in which data was collected at the XRD2 beamline. All these publications can be found (and added) in the publications area in the Virtual Unified Office (VUO) web page, after registration.

Every year, ELETTRA publishes 'ELETTRA Highlights' reporting a selection of the work done at the Laboratory during the last twelve months. In this page you will find a brief presentation of the experiments done at the XRD2 beamline and present in ELETTRA Highlights, along with other relevant results obtained at the beamline.

You can access XRD2 structures released on Protein Data Bank from our BioSync page or this link.


2024

  1. A conserved polar residue plays a critical role in mismatch detection in A-family DNA polymerases
    Clement Patterson C., Sapam Tuleshwori, Nair Deepak T.
    International Journal of Biological Macromolecules, Vol. 269, p. 131965 (2024)
    doi: 10.1016/j.ijbiomac.2024.131965 (Journal Article)
  2. A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments
    Hefny Salma M., El-Moselhy Tarek F., El-Din Nabaweya, Ammara Andrea, Angeli Andrea, Ferraroni Marta, El-Dessouki Ahmed M., Shaldam Moataz A., Yahya Galal, Al-Karmalawy Ahmed A., Supuran Claudiu T., Tawfik Haytham O.
    European Journal of Medicinal Chemistry, Vol. 274, p. 116527 (2024)
    doi: 10.1016/j.ejmech.2024.116527 (Journal Article)
  3. Antigenic determinants driving serogroup-specific antibody response to Neisseria meningitidis C, W, and Y capsular polysaccharides: Insights for rational vaccine design
    Pietri Gian Pietro, Bertuzzi Sara, Karnicar Katarina, Unione Luca, Lisnic Berislav, Malic Suzana, Miklic Karmela, Novak Matej, Calloni Ilaria, Santini Laura, Usenik Aleksandra, Romano Maria Rosaria, Adamo Roberto, Jonjic Stipan, Turk Dusan, Jiménez-Barbero Jesús, Lenac Rovis Tihana
    Carbohydrate Polymers, Vol. 341, p. 122349 (2024)
    doi: 10.1016/j.carbpol.2024.122349 (Journal Article)
  4. Benzenesulfonamide decorated dihydropyrimidin(thi)ones: carbonic anhydrase profiling and antiproliferative activity
    Aslan Hakan, Renzi Gioele, Angeli Andrea, D''Agostino Ilaria, Ronca Roberto, Massardi Maria Luisa, Tavani Camilla, Carradori Simone, Ferraroni Marta, Governa Paolo, Manetti Fabrizio, Carta Fabrizio, Supuran Claudiu T.
    RSC Med. Chem. (2024)
    doi: 10.1039/D4MD00101J (Journal Article)
  5. Development of a multi-targeted chemotherapeutic approach based on G-quadruplex stabilisation and carbonic anhydrase inhibition
    Nocentini Alessio, Di Porzio Anna, Bonardi Alessandro, Bazzicalupi Carla, Petreni Andrea, Biver Tarita, Bua Silvia, Marzano Simona, Amato Jussara, Pagano Bruno, Iaccarino Nunzia, De Tito Stefano, Amente Stefano, Supuran Claudiu T., Randazzo Antonio, Gratteri Paola
    Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 39 - 1, p. 2366236 (2024)
    doi: 10.1080/14756366.2024.2366236 (Journal Article)
  6. Diastereoselective Synthesis of High Functionalized 4-Imidazolidinone-Tetrahydro-β-Carboline Hybrids via Divergent Post-Ugi Transformation
    Morlacci Valerio, Arcadi Antonio, Aschi Massimiliano, Chiarini Marco, Demitri Nicola, Lamba Doriano, Momoli Caterina, Palombi Laura, Vece Vito
    Advanced Synthesis & Catalysis, Vol. 366 - 10, pp. 2376-2381 (2024)
    doi: 10.1002/adsc.202400133 (Journal Article)
  7. Distinct oligomerization and NADPH binding modes observed between L. donovani and human quinone oxidoreductases
    Vishwakarma Chandan, Ansari Ahmadullah, Pratap J Venkatesh
    Biochemical and Biophysical Research Communications, Vol. 690, p. 149096 (2024)
    doi: 10.1016/j.bbrc.2023.10.028 (Journal Article)
  8. Dynamics of interdomain rotation facilitates FtsZ filament assembly
    Chakraborty Joyeeta, Poddar Sakshi, Dutta Soumyajit, Bahulekar Vaishnavi, Harne Shrikant, Srinivasan Ramanujam, Gayathri Pananghat
    Journal of Biological Chemistry, Vol. 300 - 6, p. 107336 (2024)
    doi: 10.1016/j.jbc.2024.107336 (Journal Article)
  9. Experimental and Theoretical Insights into a Novel Lightfast Thiophene Azo Dye
    Diana R., Sessa L., Concilio S., Piotto S., Di Costanzo L., Carella A., Panunzi B.
    Crystals, Vol. 14 - 1, 31 (2024)
    doi: 10.3390/cryst14010031 (Journal Article)
  10. Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis
    Exertier Cécile, Salerno Alessandra, Antonelli Lorenzo, Fiorillo Annarita, Ocello Riccardo, Seghetti Francesca, Caciolla Jessica, Uliassi Elisa, Masetti Matteo, Fiorentino Eleonora, Orsini Stefania, Di Muccio Trentina, Ilari Andrea, Bolognesi Maria Laura
    J. Med. Chem., Vol. 67 - 1, pp. 402-419 (2024)
    doi: 10.1021/acs.jmedchem.3c01439 (Journal Article)
  11. Identification of the pyridoxal 5′-phosphate allosteric site in human pyridox(am)ine 5′-phosphate oxidase
    Barile Anna, Graziani Claudio, Antonelli Lorenzo, Parroni Alessia, Fiorillo Annarita, di Salvo Martino Luigi, Ilari Andrea, Giorgi Alessandra, Rosignoli Serena, Paiardini Alessandro, Contestabile Roberto, Tramonti Angela
    Protein Science, Vol. 33 - 2, p. e4900 (2024)
    doi: 10.1002/pro.4900 (Journal Article)
  12. Integrative approach in drug discovery against SARS-CoV2: a biochemical and biophysical study on the Papain-like protease
    Morasso S.
    (2024)
    (Thesis)
  13. Novel Carbonic Anhydrase Inhibitors with Dual-Tail Core Sulfonamide Show Potent and Lasting Effects for Glaucoma Therapy
    Angeli Andrea, Chelli Irene, Lucarini Laura, Sgambellone Silvia, Marri Silvia, Villano Serafina, Ferraroni Marta, De Luca Viviana, Capasso Clemente, Carta Fabrizio, Supuran Claudiu T.
    J. Med. Chem., Vol. 67 - 4, pp. 3066-3089 (2024)
    doi: 10.1021/acs.jmedchem.3c02254 (Journal Article)
  14. Palladium(II)-Imidoyl Complexes: A New Piece in the Puzzle of Organopalladium Anticancer Agents
    Bortolamiol Enrica, Novaselich Sofia, Tupini Chiara, Fagnani Sofia, Gambari Roberto, Demitri Nicola, Lampronti Ilaria, Visentin Fabiano, Scattolin Thomas
    European Journal of Inorganic Chemistry, Vol. 27 - 8, p. e202300673 (2024)
    doi: 10.1002/ejic.202300673 (Journal Article)
  15. Platinum(0)-η2-1,2-(E)ditosylethene Complexes Bearing Phosphine, Isocyanide and N-Heterocyclic Carbene Ligands: Synthesis and Cytotoxicity towards Ovarian and Breast Cancer Cells
    Compagno Nicola, Piccolo Rachele, Bortolamiol Enrica, Demitri Nicola, Rizzolio Flavio, Visentin Fabiano, Scattolin Thomas
    Molecules, Vol. 29 - 5, pp. 1-18 (2024)
    doi: 10.3390/molecules29051119 (Journal Article)
  16. Rational Design of Palladium(II) Indenyl and Allyl Complexes Bearing Phosphine and Isocyanide Ancillary Ligands with Promising Antitumor Activity
    Bortolamiol Enrica, Botter Eleonora, Cavarzerani Enrico, Mauceri Matteo, Demitri Nicola, Rizzolio Flavio, Visentin Fabiano, Scattolin Thomas
    Molecules, Vol. 29 - 2, p. 345 (2024)
    doi: 10.3390/molecules29020345 (Journal Article)
  17. Structural basis for specific inhibition of salicylate synthase from Mycobacterium abscessus
    Mori Matteo, Cocorullo Mario, Tresoldi Andrea, Cazzaniga Giulia, Gelain Arianna, Stelitano Giovanni, Chiarelli Laurent R., Tomaiuolo Martina, Delre Pietro, Mangiatordi Giuseppe F., Garofalo Mariangela, Cassetta Alberto, Covaceuszach Sonia, Villa Stefania, Meneghetti Fiorella
    European Journal of Medicinal Chemistry, Vol. 265, p. 116073 (2024)
    doi: 10.1016/j.ejmech.2023.116073 (Journal Article)
  18. Structural insights and aggregation propensity of a super-stable monellin mutant: A new potential building block for protein-based nanostructured materials
    Lucignano Rosanna, Spadaccini Roberta, Merlino Antonello, Ami Diletta, Natalello Antonino, Ferraro Giarita, Picone Delia
    International Journal of Biological Macromolecules, Vol. 254, p. 127775 (2024)
    doi: 10.1016/j.ijbiomac.2023.127775 (Journal Article)
  19. Supramolecular Hydrogels and Water Channels of Differing Diameters from Dipeptide Isomers
    Bellotto Ottavia, Scarel Erica, Pierri Giovanni, Rozhin Petr, Kralj Slavko, Polentarutti Maurizio, Bandiera Antonella, Rossi Barbara, Vargiu Attilio V., Tedesco Consiglia, Marchesan Silvia
    Biomacromolecules, Vol. 25 - 4, pp. 2476-2485 (2024)
    doi: 10.1021/acs.biomac.3c01439 (Journal Article)
  20. Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety
    Al-Matarneh Cristina M., Pinteala Mariana, Nicolescu Alina, Silion Mihaela, Mocci Francesca, Puf Razvan, Angeli Andrea, Ferraroni Marta, Supuran Claudiu T., Zara Susi, Carradori Simone, Paoletti Niccolò, Bonardi Alessandro, Gratteri Paola
    J. Med. Chem., Vol. 67 - 4, pp. 3018-3038 (2024)
    doi: 10.1021/acs.jmedchem.3c02190 (Journal Article)
  21. Tau-S214 Phosphorylation Inhibits Fyn Kinase Interaction and Increases the Decay Time of NMDAR-mediated Current
    Jos Sneha, Poulose Roshni, Kambaru Archanalakshmi, Gogoi Hemanga, Dalavaikodihalli Nanjaiah Nandakumar, Padmanabhan Balasundaram, Mehta Bhupesh, Padavattan Sivaraman
    Journal of Molecular Biology, Vol. 436 - 4, p. 168445 (2024)
    doi: 10.1016/j.jmb.2024.168445 (Journal Article)
  22. The dopamine D2 receptors antagonist Veralipride inhibits carbonic anhydrases: solution and crystallographic insights on human isoforms
    Angeli Andrea, Ferraroni Marta, Capasso Clemente, Supuran Claudiu T.
    Chemistry – An Asian Journal, Vol. 19 - 8, p. e202400067 (2024)
    doi: 10.1002/asia.202400067 (Journal Article)
  23. Unexpected Single-Ligand Occupancy and Negative Cooperativity in the SARS-CoV-2 Main Protease
    Albani Simone, Costanzi Elisa, Hoang Gia Linh, Kuzikov Maria, Frings Marcus, Ansari Narjes, Demitri Nicola, Nguyen Toan T., Rizzi Valerio, Schulz Jörg B., Bolm Carsten, Zaliani Andrea, Carloni Paolo, Storici Paola, Rossetti Giulia
    J. Chem. Inf. Model., Vol. 64 - 3, pp. 892-904 (2024)
    doi: 10.1021/acs.jcim.3c01497 (Journal Article)
Last Updated on Friday, 24 September 2021 08:45